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BPA causes DNA damage to and proliferation of breast cells

Environment
Articles & Research

A study by Pfeifer et al, published in Environmental Health Perspectives, found that even at the low doses commonly present in humans, BPA significantly promoted DNA damage and caused proliferation of breast mammary cells.

Humans are exposed to low-dose bisphenol A (BPA) through plastic consumer products and dental sealants containing BPA.

Another study by Dairkee et al, published in the journal Carcinogenesis,  found that BPA disrupts checkpoints that normally cause cell death and that limit cell proliferation. Since BPA binds to estrogen receptors and stimulates DNA synthesis in breast cancer cells (), a role for BPA in breast carcinogenesis has been considered possible.